Derbyshire Royal Infirmary (DRI) was established in 1810, In 1890 a Typhoid outbreak swept through the hospital, and the building’s design was blamed. The hospital is entirely demolished, a year later Queen Victoria laid the foundation stone in 1894, and its main features were its 'Onion' shaped domed towers and its central corridor which ran the length of the hospital.

The hospital was expanded at several points in the 20th century, the most visible being the still used Wilderslowe Tower and the now disused A+E building built in 1970

In the late 90s, the NHS drew up a dramatic plan to consolidate the services of two hospitals on a new site

There are no official plans to redevelop the now redundant Derbyshire Royal Infirmary, the land is covered by a large regeneration plan which will expand Derby's city centre but this seems to be a way off in the future.